猪水肿病疫苗的研究进展Research Progress of Vaccines against Porcine Edema Disease
杨玲媛;任文凯;王文策;杨丹丹;印遇龙;
摘要(Abstract):
就近几年来猪水肿病的疫苗研究做一个全面的综述,为该病的预防及疫苗的研制提供理论依据。
关键词(KeyWords): 大肠杆菌;水肿病;毒力因子;疫苗;进展
基金项目(Foundation): 国家“十一五”支撑计划项目(2008BADA7B00);; 国家“973”项目(2009CB118800)
作者(Author): 杨玲媛;任文凯;王文策;杨丹丹;印遇龙;
Email:
DOI: 10.13989/j.cnki.0517-6611.2011.09.227
参考文献(References):
- [1]MAKINO S,WATARAI M,TABUCHI H,et al.Genetically modified Shigatoxin 2e(Stx2e)producing Escherichia coli is a vaccine candidate for por-cine edema disease[J].Microb Pathog,2001,31:1-8.
- [2]林艺远,刘国平,杨明柳,等.猪水肿病发病机理研究进展[J].动物医学进展,2006,27(7):10-15.
- [3]蔡宝祥.家畜传染病学[M].4版.北京:中国农业出版社,2001:46-52.
- [4]SHANKS P L.An unusual condition affecting the digestive organs of thepig[J].Vet Rec,1938,50:356-358.
- [5]TAKESHI M,EIJI T,TOSHIO S,et al.Production of double repeated Bsubunit of Shiga toxin 2e at high levels in transgenic lettuce plants as vac-cine material for porcine edema disease[J].Transgenic Res,2010:421-427.
- [6]REN W,LIU J,PENG Y.Prediction of the B cell epitope for the SLT-IIeBof Escherichia coli eliciting edema of piglet[J].Sichuan Animal&Veteri-nary Sciences,2009,8:24-25.
- [7]FRASERME,CHERNEYMM,MARCATOP,et al.Bindingof adeninetoStx2,the protein toxin from Escherichia coli O157:H7[J].Acta CrystallogrSect F Struct Biol Cryst Commun,2006,62:627-630.
- [8]CHENG D,SUN H,XU J,et al.Prevalence of fimbial colonization factorsF18ab and F18ac in Escherichia coli isolates from weaned piglets with edemaand/or diarrhea in China[J].Vet Microbiol,2005,110(1/2):135-139.
- [9]MCXLEY R A.Edema disease[J].Vet Clin North Am Food Anim Pract,2000,16(1):175-185.
- [10]BERTSCHINGER H U,BAEHMANN M,POSPISEHIL A,et al.Adhesivefimbriae produeed in vivo by Escherichia coli 0139:K12:H1 associatedwith enterotoxaemia in pigs[J].Vet Microbiol,1990,25(4):267-281.
- [11]BERTSEHINGER H U,GYLES C L.Escheriehia coli in domestic animalsand humans[J].Odema Disease of Pigs,1994,21(3):193-219.
- [12]RIPPINGER P,BERTSCHINGER H U,IMBERECHTS H,et al.Designa-tions F18ab and F18ac for the related fimbrial types F107,2134P and8813 of Eacherichia coli isolated from porcine post-weaning diarrhoea andfrom oedema disease[J].Vet Microbiol,1995,45(4):281-295.
- [13]FEKETE P Z,OERARDIN J,JACQUEMIN E,et a1.Replicon typing ofF18 fimbriae encoding plasmids of enterotoxigenic and verotoxigenicEacherichia coli strains from porcine postweaning diarrhoea and oedemadisease[J].Vet Microbiol,2002,85(3):275-284.
- [14]徐建生.猪水肿病毒素保护性抗原的菌体表面表达及其黏膜免疫反应[D].扬州:扬州大学,2002:7-18.
- [15]SPEIRS J I,STAVRIC S,KONOWALCHUK J.Assay of Escherichia coliheat-labile enterotoxin with vero cells[J].Infect Immun,1977,16(2):617-622.
- [16]DOBRESCU L,HUYGELEN C.Susceptibility of the mouse intestine toheat-stable enterotoxin produced by enteropathogenic Escherichia coli ofporcine origin[J].Appl Microbiol,1973,26(3):450-451.
- [17]刘国平,吴斌,刘梦元,等.水肿毒素SLI-lle A的克隆与序列分析[J].动物医学进展,2004,25(1):122-125.
- [18]黄志琴,黄国伟,叶春芳,等.猪水肿病多价灭活苗应用效果试验[J].中国兽医杂志,1999,23(20):58.
- [19]杨威,谢永平,陈泽祥,等.猪水肿病大肠杆菌多价油乳剂灭活苗的研究[J].广西畜牧兽医,2007,23(5):199-200.
- [20]穆永才,刘文韬,罗天瑶,等.防治齐市地区仔猪水肿病多价油乳剂灭活疫苗的研制及应用[J].黑龙江畜牧兽医,2007(12):96-97.
- [21]马忠英,马慧凤,马慧龙.应用“母仔双免法”防控仔猪水肿病[J].疫病防治,2007(9):54.
- [22]成大荣,徐建生,王秋娟,等.大肠杆菌F18ac菌毛FedA蛋白的表达与鉴定[J].动物医学进展,2005,26(2):51-55.
- [23]成大荣,徐建生,丁爱云,等.大肠埃希氏菌F18菌毛FedF蛋白的表达与鉴定[J].中国兽医科技,2005,35(4):272-276.
- [24]SMEDS A,PERTOVAARA M,TIMONEN T,et al.Mapping the bindingdomain of the F18 fimbrial adhesion[J].Infect Immun,2003,71:2163-2172.
- [25]刘国平,郭爱珍,吴斌,等.致猪水肿病大肠杆菌鄂E株菌毛F18基因FedF亚基的克隆、表达及其生物学特性[J].中国兽医学报,2008,28(5):479-484.
- [26]林艺远,刘国平,吴斌,等.致猪水肿病大肠杆菌鄂E株SLT-IIeB基因的克隆、序列分析及原核表达[J].华中农业大学学报,2006,25(5):474-478.
- [27]MARCATO P,MULVEY G,ARMSTRONG G D.Cloned Shiga toxin 2 Bsubunit induces apoptosis in Ramos Burkitt's lymphoma B cells[J].InfectImmun,2002,70(3):1279-1286.
- [28]刘国平,吴斌,林艺远,等.大肠杆菌Ee株SLT-IIeB与FedF基因的融合表达及表达产物的免疫原性研究[J].微生物学报,2007,47(6):1044-1049.
- [29]任文凯,张关玲,刘建飞,等.猪水肿病大肠杆菌主要毒力因子的B细胞表位预测与验证[J].中国兽医杂志,2010,46(8):34-35.
- [30]AORIGELE,WANG C J,YU J E,et al.Sterilization effects of bacterial in-hibitor on Escherichia coli in cattle manure compost[J].Agricultural Sci-ence&Technology,2008,9(6):154-156.
- [31]郭利英.断奶仔猪水肿病的诊治[J].畜牧与饲料科学,2009,30(6):68.
- [32]PANG XH,CHUXL,SUJQ,etal.Screeningandefficacyobservationoftraditional Chinese medicine against chicken pathogenic Escherichia coli[J].Agricultural Science&Technology,2009,10(1):140-144.
- [33]陈文利.仔猪水肿病的防治[J].畜牧与饲料科学,2009,30(6):69.
- [34]LUO Y,CHENG J G,ZHENG S H,et al.Plasmid DNA analysis of patho-genic Escherichia coli in musk deer[J].Agricultural Science&Technolo-gy,2009,10(3):22-25.
- [35]哈斯巴特尔,宋会良.猪水肿病的诊断与科学防治[J].畜牧与饲料科学,2009,30(7-8):115-117.