牛蒡子醇提物抑制小鼠宫颈癌U14生长的研究Study on Effect of the Extract from Fructus arctii on the Uterine Cervical Carcinoma(U_(14)) Growth of Mice Harboring Tumor
耿果霞;龙玲;李青旺;王建华;
摘要(Abstract):
通过建立小鼠宫颈癌U14实体瘤与腹水瘤2种动物模型,观察牛蒡子醇提物对实体瘤抑瘤率和腹水瘤生命延长率的影响。结果发现,以阴性对照组为基础,牛蒡子醇提物3个剂量组及环磷酰胺(CTX)阳性对照组实体瘤各组抑瘤率分别为31.7%、49.7%、57.4%和83.6%(P<0.01);腹水瘤各组生命延长率分别为39.8%、46.6%、62.5%和91.6%(P<0.01)。表明牛蒡子醇提物对小鼠宫颈癌U14的生长有一定的抑制作用。
关键词(KeyWords): 牛蒡子;U14;实体瘤;腹水瘤
基金项目(Foundation):
作者(Author): 耿果霞;龙玲;李青旺;王建华;
Email:
DOI: 10.13989/j.cnki.0517-6611.2006.21.059
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