微波消解-电感耦合等离子体质谱法测定怀牛膝中重金属元素含量Determination on Heavy Metals Content of Achyranthes bidentata Blume through Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
李宇伟;王新民;连瑞丽;魏志华;介晓磊;陈士林;
摘要(Abstract)：
[目的]建立微波消解-电感耦合等离子体质谱(ICP-MS)的方法,测定怀牛膝中铅、镉、汞、砷含量。[方法]优化ICP-MS的操作条件,将样品进行微波消解,以114In作为内标,补偿基体效应,采用ICP-MS法同时测定上述4种元素。[结果]对于所测元素,标准曲线的相关系数r>0.9995,回收率为96.7%~106.4%,RSD<11.2%;样品测定结果表明,供试怀牛膝药材重金属超标现象较为严重。[结论]该研究建立的微波消解-ICP-MS法简便、快速、准确、灵敏度高,可为不同产地不同种类的中药材提供重金属含量的测定方法,用于中药材的质量控制。
关键词(KeyWords)： 微波消解;电感耦合等离子体质谱(ICP-MS);怀牛膝;重金属
基金项目(Foundation): 中国第41批博士后科学基金面上项目(20070410616);; 河南省杰出青年科学基金项目(074100510018)
作者(Author): 李宇伟;王新民;连瑞丽;魏志华;介晓磊;陈士林;
Email:
DOI:
参考文献(References)：
- [1]YI XH,LUYT.Study on residues of pesticides and heavy metals inLigusticumwallichiiFranch and other seven kinds of traditional Chinese medicine[J].Re-search and Practice of Chinese Medicines,2004,18(3):7-9.
- [2]CAO Z Q.Trace element and Chinese medicine[M].Beijing:Traditional ChineseMedicine Press,1996:1-54.
- [3]QIU Z C,YANGMF,HE Y,et al.Measuring trace elements in alisma orientalis(Sam)juzep from four districts with ICP-MS[J].Fujian Analysis&Testirg,2003,12(2):1739-1740.
- [4]CHEN H,LIANG P,HU B,et al.The application of inductively coupled plasmaatomic emission spectrometry/mass spectrometry in the trace elements and spe-ciation analysis of traditional Chinese medicine[J].Spectroscopy and SpectralAnalysis,2002,22(6):1019.
- [5]LUL P,CAO C.Study on quality in lumbricus from different origin[J].Guang-dong Trace Elements Science,2004,11(6):50.
- [6]WANG X M,ZHANG Z Y,LI Y W,et al.Standard operating procedure(SOP)for cultivated techniques of Achyranthes bidentata Blume.under good agriculturepractice(GAP)[J].Journal of Anhui Agricultural Sciences,2006,34(5):922-923.
- [7]WENHM,CHEN X H,DONGT X,et al.Determination of heavy metals in fourtraditional Chinese medicines by ICP-MS[J].China Journal of Chinese MateriaMedica,2006,31(16):1314-1317.