由昭红;

• 1:枣庄学院

摘要(Abstract)：

综述F18菌毛的一般特性、表达和提取、相关血清型和毒力因子、亚单位及基因调控等。

关键词(KeyWords)： 仔猪断奶腹泻;F18菌毛;产肠毒素型大肠杆菌

Abstract:

Keywords:

基金项目(Foundation): 浙江省科技厅资助项目(2003C32002)

作者(Author): 由昭红;

Email:

DOI:

参考文献(References)：

• [1]KWON D,CHIO C,JUNG T,et al.Genotypic prevalence of the fimbrial adhe-sions(F4,F5,F6,F41 and F18)and toxins(LT,STa,STb and STx2e)inEs-cherichia coliisolated from postweaning pigs with diarrhoea or oedema disease inKorea[J].Vet Rec,2002,150(2):35-37.
• [2]BERTSCHINGER HU,BACHMANN M,METTLER C,et al.Adhesive fimbriaeexpressed only in vivo byEscherichia colicausing edema disease in pigs.pro-ceed.10th Conger.Int.pig Vet Soc,(1988)August 14-17.Rio de Janeiro.Brazil,p.115.
• [3]BERTSCHINGER HU,BACHMANN M,METTLER C,et al.Adhesive fimbriaeproduced in vivo byEscherichia coliO139:K12(B):H1 associated with entero-toxaemia in pigs[J].Vet Microbiol,1990,25:267-281.
• [4]NAGY B,CASEYTA,MOONHW.Phenotype and genotype ofEscherichia coliisolated from pigs with postweaning diarrhea in Hungary[J].Clin Microbiol,1990,28:651-653.
• [5]CASEY T A,NAGY B,MOON H W.Pathogenicity of porcine enterotoxigenicEscherichia colithat do not express K88,K99,F41 or p987P adhesions[J].Am JVet Res,1992,53:1488-1492.
• [6]IMBERECHTS H,DE GREVE H,SCHLICKER C,et al.Characterization of F107fimbriae ofEscherichia coli107/86,which causes edema disease in pigs,andnucleotide sequence of the F107 major fimbrial subunit gene,fedA[J].InfectImmun,1992,60:1963-1971.
• [7]RIPPINGER P,BERTSCHINGER H U,IMBERECHTS H,et al.DesignationsF18ab and F18ac for the related fimbrial types F107,2134P and 8813 ofEs-cherichia coliisolated from porcine postweaning diarrhoea and from oedema dis-ease[J].Vet Microbiol,1995,45:281-295.
• [8]WITTIG W,PRAGER RM,STAMM W,et al.Expression and plasmid transfer ofgenes coding for the fimbrial antigen F107 in porcineEscherichia colistrains[J].Zentbl Bakteriol,1994,281:130-139.
• [9]ERIK H,PETER W,ELISABETH M,et al.Structural analysis of F18 fimbriaeexpressed by porcine toxigenicEscherichia coli[J].Journal of Structural Biolo-gy,2000,132:241-250.
• [10]郭玉广,高崧,刘秀梵.致断奶仔猪腹泻、水肿病大肠杆菌F18菌毛a因子单克隆抗体的研制及其初步应用[J].中国兽医学报,2004,24(6):541-544.
• [11]HIDE E J,CONNAUGHTON I D,DRIESEN S J,et al.The prevalence of F107fimbriae and their association with Shiga-like toxin II inEscherichia colistrainsfrom weaned Australian pigs[J].Vet Microbiol,1995,47:235-243.
• [12]严振龙,王欣之,姜连连,等.F107(F18ab)菌毛的提取提纯及鉴定[J].中国兽药杂,2002,36(7):30-32.
• [13]FEKETE P Z,GERARDIN J,JACQUEMIN E,et al.Replicon typing of F18 fim-briae encoding plasmids of enterotoxigenic and verotoxigenicEscherichia colistrains from porcine postweaning diarrhea and oedema disease[J].Vet Microbi-ol,2002,85(3):275-284.
• [14]成大荣,徐建生,刘秀梵.黏附素菌毛F18的研究进展[J].中国预防兽医学报,2004,26(5):388-390.
• [15]AMORIM C R,MATSUURA M S,ROSA J C,et al.Purification and characteri-zation of the fimbria F18ac(2134P)isolated from enterotoxigenicEscherichiacoli(ETEC)[J].Vet Microbiol,2000,76:41-49.
• [16]BOSWORTH B T,DEAN-NYSTROM E A,CASEYT A,et al.Differentiation ofF18ab+from F18ac+Escherichia coliby single-strand conformational polymor-phism analysis of the major fimbrial subunit gene(fedA)[J].Clin Diagn LabImmunol,1998,5:299-302.
• [17]卢银华,成大荣,徐建生,等.大肠杆菌F18菌毛A亚单位(fecA)的克隆与序列测定[J].江苏农业研究,2001,22(3):49-61.
• [18]TIELS P,VERDONCK F,SMET A.The F18 fimbrial adhesin FedF is highlyconserved among F18+Escherichia coliisolates[J].Vet Microbiol,2005,110:277-283.
• [19]VERDONCK F,COX E,GODDEERIS B M.F4 fimbriae expressed by porcineenterotoxigenicEscherichia coli,an example of an eccentric fimbrial system[J].J Mol Microbiol Biotechnol,2004,7:155-169.
• [20]SMEDS A,HEMMANN K,JAKAVA-VILJANEN M,et al.Characterization ofthe adhesion ofEscherichia coliF18 fimbriae[J].Infect Immun,2001,69:7941-7945.
• [21]VERDONCK F,COX E,SCHEPERS E,et al.Conserved regions in the se-quence of the F4(K88)fimbrial adhesin FaeG suggest a donor strand mecha-nism in F4 assembly[J].Vet Microbiol,2004,102:215-225.
• [22]THANASSI DG,HULTGREN S J.Assembly of complex organelles:pilus bio-genesis in gram-negative bacteria as a model system[J].Methods,2000,20:111-126.
• [23]SAUER F G,KNIGHT S D,WAKSMAN G,et al.PapD-like chaperones andpilus biogenesis[J].Semin Cell Dev Biol,2000,11:27-34.
• [24]HUNG D L,KNIGHT S D,HULTGREN S J.Probing conserved surfaces on Pa-pD[J].Mol Microbiol,1999,31:773-783.
• [25]BUTS L,BOUCKAERT J,DE GENST E,et al.The fimbrial adhesin F17-G ofenterotoxigenic Escherichia coli has an immunoglobulin-like lectin domain thatbinds N-acetylglucosamine[J].Mol Microbiol,2003,49:705-715.
• [26]ZAVIALOV A V,BERGLUND J,PUDNEY A F.Structure and biogenesis of thecapsular F1 antigen fromYersinia pestis:preserved folding energy drives fiberformation[J].Cell,2003,113:587-596.
• [27]SMEDS A,PERTOVAARA M,TIMONENT,et al.mapping the binding domainof the F18 fimbrial adhesion[J].Infect Immun,2003,71:2163-2172.
• [28]NAGY B,WHIPP S C,IMBERECHTS H,et al.Biological relationship betweenF18ab and F18ac fimbriae of enterotoxigenic and verotoxigenicEscherichia colifrom weaned pigs with oedema disease or diarrhoea[J].M icrobiol Pathog,1997,22(1):1211-1219.
• [29]RUTHK,OLOF S,PATEICIA C.Presence of F107,2134 and Av24 fimbriae onstrains ofEscherichia coliisolates from Swedish piglets with diarrhea[J].VetMicrobiol,1995,43:123-129.
• [30]ALex Souza da Silva,Georgio Freesz Valadares,Mario Paulo Amante Penatti.Escherichia colistrains from edema disease:O serogroups,and genes for Shigatoxin enterotoxins,and F18 fimbriae[J].Vet Microbiol,2001,80:227-233.
• [31]BLANCO M,BLANCO J E,GONZALEZ E A,et al.Genes encoding for entero-toxins in porcineEscherichia colistrains belonging to different O:K:Hserotypes:relationship with toxi phenotypes[J].Clin Microbiol,1997,35:2958-2963.
• [32]PRAGER R,BAUERFEIND R,TIETZE E,et al.Prevalence and deletion typesof the pathogenicity island ETT2 amongEscherichia colistrains from oedemadisease and colibacillosis in pigs[J].Vet Microbiol,2004,99:287-294.
• [33]JERSE A E,YU J,TALL B D,et al.A genetic locus of enteropathogenicEs-cherichia colinecessary for the production of attaching and effacing lesions ontissue culture cells[J].Proc Natl Acad Sci USA,1990,87:7839-7843.
• [34]MCDANIEL T K,KAPER J B.A cloned pathogenicity island from en-teropathogenicEscherichia coliconfers the attaching and effacing phenotype onE.coliK-12[J].Mol Microbiol,1997,23:399-407.
• [35]GOPHNA U,OELSCHLAEGER T A,HACKER J,et al.YersiniaHPI in sep-ticemicEscherichia colistrains isolated from diverse hosts[J].FEMSMicrobiolLett,2001,196:57-60.
• [36]YU J,KAPER J B.Cloning and characterization of theeaegene of enterohaem-orrhagicEscherichia coliO157:H7[J].Mol Microbiol,1992,6:411-417.
• [37]LAI L C,WAINWRIGH L A,STONE K D,et al.A third secreted protein that isencoded by the enteropathogenicEscherichia colipathogenicity island is re-quired for transduction of signals and for attaching and effacing activities inhost cells[J].Infect Immun,1997,65:2211-2217.
• [38]CHENG D R,SUN H C,XU J S,et al.PCR detection of virulence factor genesinEscherichia coliisolates fromweaned piglets with edema disease and/or di-arrhea in China[J].Vet Microbiol,2006,115(4):320-328.
• [39]MAINIL J G,JACQUEMIN E,POHL P,et al.DNA sequences coding for theF18 fimbriae and AIDA adhesin are localised on the same plasmid inEs-cherichia coliisolates from piglets[J].Vet Microbiol,2002,86(4):303-311.
• [40]ZHAO L,CHEN X,XU X,et al.Analysis of the AIDA-I gene sequence andprevalence inEscherichia coliisolates from pigs with post-weaning diarrhoeaand oedema disease[J].Vet Microbiol.(2007)(已录用).
• [41]成大荣,徐建生,孙怀昌,等.大肠杆菌F18菌毛及其亚型的PCR鉴定[J].微生物学报,2004,44(5):683-685.
• [42]OSEK J.Clonal analysis ofEscherichia colistrains isolated from pigs with post-weaning diarrhea by pulsed-field gel electrophoresis[J].FEMS MicrobiologyLetters,2000,186:327-331.
• [43]YOKOYAMA H,HASHI T,UMEDA K.Effect of oral egg antibody in experi-mental F18+Escherichia coliinfection in weaned pigs[J].Vet Med Sci,1997,10:917-21.
• [44]ZUNIGA A,YOKOYAMA H,RIPPINGER P A,et al.Reduced intestinal colo-nization with F18-positive enterotoxigenicEscherichia coliin weaned pigs fedchicken egg antibody against the fimbriae[J].Immunology and Medical Micro-biology,1997,18:153-167.
• [45]FRYDENDAHL K,JENSEN T K,ANDERSEN J S,et al.Association betweenthe porcineEscherichia coliF18receptor genotype and phenotype and suscep-tibility to colonization and postweaning diarrhea caused byE.coliO138:F18[J].Vet Microbiol,2003,93:39-51.
• [46]SNOECK V,VERDONCK F,COXA E.Inhibition of adhesion of F18+Es-cherichia colito piglet intestinal villous enterocytes by monoclonal antibody a-gainst blood group H-2 antigen[J].Vet Microbiol,2004,100:241-246.
• [47]徐建生,成大荣.选择优良菌用于仔猪水肿病疫苗的改进[J].中国预防兽医学报,2002,24(4):297-300.
• [48]ZUREK L,SCHAL C.Evaluation of the German cockroach(Blattella germani-ca)as a vector for verotoxigenicEscherichia coliF18 in confined swine pro-duction[J].Vet Microbiol,2004,101:263-267.