空肠弯曲菌flaA基因序列及功能预测分析Analysis of Gene Sequence and Function Prediction of flaA in Campylobacter jejuni
訾臣;曾德新;蒋鲁岩;袁飞;蒋原;薛峰;
摘要(Abstract)：
[目的]对空肠弯曲菌空肠弯曲菌flaA基因的序列及功能进行预测分析。[方法]分析了多个空肠弯曲菌flaA核酸及氨基酸序列组成和序列差异性;预测分析了flaA基因密码子使用偏好性、蛋白结构和功能域、Fla A与相关功能蛋白的互作情况。[结果]不同菌株的flaA基因序列存在差异性,且差异主要存在于序列的中间区域。不同空肠弯曲菌菌株的同一基因在密码子选择上存在差异。Fla A与多个蛋白存在不同形式的相互作用。[结论]该研究可为空肠弯曲菌flaA基因序列分析和功能研究应用提供基础和依据。
关键词(KeyWords)： 空肠弯曲菌;flaA基因;密码子偏好;蛋白结构域;蛋白互作
基金项目(Foundation): 国家质量监督检验检疫总局科技计划项目(2016IK131); 江苏省出入境检验检疫局科研项目(2017KJ46); 南京农业大学科研资助项目(804121); 质检公益性行业科研专项(201510038)
作者(Author): 訾臣;曾德新;蒋鲁岩;袁飞;蒋原;薛峰;
Email:
DOI: 10.13989/j.cnki.0517-6611.2017.32.050
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