牛磺酸对体外培养大鼠睾丸间质细胞睾酮分泌的影响Effect of the Taurine on Testosterone Secretion of Culturing Rat Leydig Cells in Vitro
杨建成;冯颖;吴高峰;孙长勉;胡建民;
摘要(Abstract)：
通过在基础培养液(DMEM)中添加不同水平的牛磺酸和人绒毛膜促性腺激素(HCG),研究了牛磺酸(1～100 mg/L)对体外培养大鼠睾丸间质细胞睾酮分泌性能的影响。结果表明,牛磺酸(1～100 mg/L)对体外培养大鼠睾丸间质细胞睾酮的分泌有显著的促进作用(P<0.01);而对HCG刺激的睾丸间质细胞睾酮的分泌表现出双相作用,低剂量牛磺酸对其有明显的促进作用(P<0.05),高剂量则有显著的抑制作用(P<0.05)。
关键词(KeyWords)： 牛磺酸;睾丸间质细胞;体外培养;睾酮分泌;大鼠
基金项目(Foundation): 国家自然科学基金项目(30371048)
作者(Author): 杨建成;冯颖;吴高峰;孙长勉;胡建民;
Email:
DOI: 10.13989/j.cnki.0517-6611.2007.15.068
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