植物次生生长相关MYB转录因子研究进展Research Advances in the Secondary Growth-associated MYB Transcription Factors in Plants
薛英喜;魏建华;姜廷波;王宏芝;
摘要(Abstract):
林木的次生木质部是重要的再生生物能源,在人类的生产生活中具有重要意义。作为植物中最大的转录因子家族之一,MYB转录因子在次生壁合成转录调控过程中发挥重要的作用。目前许多主要的次生壁合成相关MYB转录因子已被分离鉴定。AC顺式作用元件是MYB转录因子与木质素合成基因结合的重要元件。该研究综述了MYB转录因子结构及进化,介绍了转录激活因子与抑制因子如何调控次生壁的合成,并对MYB转录因子的转录后修饰、进化的保守性及其转录调控网络进行了阐述。
关键词(KeyWords): MYB转录因子;次生生长转录调控网络;AC顺式作用元件;转录后修饰;进化保守性
基金项目(Foundation): 国家高技术研究发展计划(2011AA100201);; 国家重点基础研究发展计划(2012CB114501)
作者(Author): 薛英喜;魏建华;姜廷波;王宏芝;
Email:
DOI: 10.13989/j.cnki.0517-6611.2012.13.007
参考文献(References):
- [1]KLEMPNAUER K H,GONDA T J,BISHOP J M.Nucleotide sequence ofthe retroviral leukemia gene v-myb and its cellular progenitor c-myb:the ar-chitecture of a transduced oncogene[J].Cell,198,231:453-463.
- [2]PAZ-ARES J,GHOSAL D,WIENAND U,et al.The regulatory c1 locus ofZea mays encodes a protein with homology to myb proto-oncogene productsand with structural similarities to transcriptional activators[J].The EMBOJournal,19876,(12):3553-3558.
- [3]DUBOS CS,TRACKE R,GROTEWOLD Ee,t al.MYB transcription factorsin Arabidopsis[J].Trends in Plant Science,2010,15(10):573-581.
- [4]WILKINS O,NAHAL H,FOONG Je,t al.Expansion and Diversification ofthe Populus R2R3-MYB Family of Transcription Factors[J].Plant Physiol-ogy,2009,149:981-993.
- [5]FRAMPTON J.Myb transcription factors:their role in growth,differentia-tion and disease[M].Netherlands:Kluwer Academic Publishers,2004:6-8.
- [6]KRANZ H D,DENEKAMP M,GRECO R,et al.Towards functional charac-terisation of the members of the R2R3-MYB gene family from Arabidopsisthaliana[J].Plant Journal,1998,16(2):263-276.
- [7]DUBOS C,GOURRIEREC J L,BAUDRY A,et al.MYBL2 is a new regula-tor of flavonoid biosynthesis in Arabidopsis thaliana[J].Plant Journal,20085,5:940-953.
- [8]LU S X,KNOWLES S M,ANDRONIS C,et al.CIRCADIAN CLOCK AS-SOCIATED1 and LATE ELONGATED HYPOCOTYL function synergisti-cally in the circadian clock of Arabidopsis[J].Plant Physiology,2009,150:834-843.
- [9]HOSODA KI,MAMURA A,KATOH E,et al.Molecular structure of theGARP family of plant Myb-related DNA binding motifs of the Arabidopsisresponse regulators[J].Plant Cell,2002,14:2015-2029.
- [10]HAGA N,KATO K,MURASE Me,t al.R1R2R3-MYB proteins positivelyregulate cytokinesis through activationof KNOLLE transcription in Arabi-dopsis thaliana[J].Development,200,7134(6):1101-1110.
- [11]STRACKE R,WERBER M,WEISSHAAR B.The R2R3-MYB gene fam-ily in Arabidopsis thaliana[J].Current Opinion in Plant Biology,20014,(5):447-456.
- [12]CHEN Y H,YANG X Y,HE Ke,t al.The MYB transcription factor super-family of Arabidopsis:expression analysis and phylogenetic comparisonwith the rice MYB family[J].Plant Molecular Biology,2006,60:107-124.
- [13]MATUS J T,AQUEA M,ARCE-JOHNSON P.Analysis of the grape MYBR2R3 subfamily reveals expanded wine quality-related clades and con-served gene structure organization across Vitis and Arabidopsis genomes[J].BMC Plant Biology,20088,:83.
- [14]YANG C,XU Z,SONG J,et al.Arabidopsis MYB26/MALE STERILE35regulates secondary thickening in the endothecium and is essential for an-ther dehiscence[J].Plant Cell,200,719:534-548.
- [15]STEINER-LANGE S,UNTE U S,ECKSTEIN Le,t al.Disruption of Arabi-dopsis thaliana MYB26 results in male sterility due to non-dehiscent an-thers[J].Plant Journal,2003,34:519-528.
- [16]MITSUDA N,SEKI M,SHINOZAKI K,et al.The NAC transcription fac-tors NST1 and NST2 of Arabidopsis regulates secondary wall thickeningand are required for anther dehiscence[J].Plant Cell,2005,17:2993-3006.
- [17]ZHONG R Q,RICHARDSON E A,YE Z H.The MYB46 TranscriptionFactor is a Direct Target of SND1 and Regulates Secondary Wall Biosyn-thesis in Arabidopsis[J].Plant Cell,200,719:2776-2792.
- [18]MCCARTHY R L,ZHONG R Q,YE Z H.MYB83 is a direct target ofSND1 and acts redundantly with MYB46 in the regulation of secondarycell wall biosynthesis in Arabidopsis[J].Plant Cell Physiology,2009,50(11):1950-1964.
- [19]PATZLAFF A,MCLNNIS S,COURTENAY Ae,t al.Characterisation of apine MYB that regulates lignification[J].Plant Journal,200,336:743-745.
- [20]BOMAL C,BEDON F,CARON S,et al.Involvement of Pinus taeda MYB1and MYB8 in phenylpropanoid metabolism and secondary cell wall bio-genesis:a comparative in planta analysis[J].Journal of Experimental Bot-any,20085,9(14):3925-3939.
- [21]MCCARTHY R L,ZHONG R Q,FOWLER Se,t al.The poplar MYB tran-scription factors,PtrMYB3 and PtrMYB20,are involved in the regulationof secondary wall biosynthesis[J].Plant Cell Physiology,2010,51(6):1084-1090.
- [22]GOICOECHEA M,LACOMBE E,LEGAY S,et al.EgMYB,2a new tran-scriptional activator from Eucalyptus xylemr,egulates secondary cell wallformation and lignin biosynthesis[J].Plant Journal,20054,3:553-567.
- [23]ZHOU J L,LEE C H,ZHONG R Qe,t al.MYB58 and MYB63 are tran-scriptional activators of the lignin biosynthetic pathway during secondarycell wall formation in Arabidopsis[J].Plant Cell,2009,21:248-266.
- [24]ZHONG R Q,LEE C H,ZHOU J L,et al.A battery of transcription factorsinvolved in the regulation of secondary cell wall biosynthesis in Arabidop-sis[J].Plant Cell,2008,20:2763-2782.
- [25]NEWMAN L J,PERRAZA D EJ,UDA Le,t al.Involvement of the R2R3-MYB,AtMYB61i,n the ectopic lignification and dark-photomorphogeniccomponents of the det3 mutant phenotype[J].Plant Journal,2004,37:239-250.
- [26]BOREVITZ J O,XIA Y,BLOUNT J,et al.Activation tagging identifies aconserved MYB regulator of phenylpropanoid biosynthesis[J].Plant Cell,2000,12:2383-2394.
- [27]TAMAGNONE L,MERIDA A,PARR A,et al.The AmMYB308 and Am-MYB330 transcription factors from Antirrhinum regulate phenylpropanoidand lignin biosynthesis in transgenic tobacco[J].Plant Cell,1998,10:135-154.
- [28]JIN H,COMINELLI E,BAILEY Pe,t al.Transcriptional repression by At-MYB4 controls production of UV-protecting sunscreens in Arabidopsis[J].The EMBO Journal,2000,19(22):6150-6161.
- [29]PRESTON J,WHEELER J,HEAZLEWOOD Je,t al.AtMYB32 is requiredfor normal pollen development in Arabidopsis thaliana[J].Plant Journal,20044,0:979-995.
- [30]FORNALE’S,SONBOL F M,MAES T,et al.Down-regulation of themaize and Arabidopsis thaliana caffeic acid O-methyl-transferase genes bytwo new maize R2R3-MYB transcription factors[J].Plant Molecular Biol-ogy,20066,2:809-823.
- [31]SONBOL F M,FORNALS,CAPELLADES M,et al.The maize Zm-MYB42 represses the phenylpropanoid pathway and affects the cell wallstructurec,omposition and degradability in Arabidopsis thaliana[J].PlantMolecular Biology,2009,70:283-296.
- [32]FORNALS,SHI X,CHAI C,et al.ZmMYB31 directly represses maizelignin genes and redirects the phenylpropanoid metabolic flux[J].PlantJournal,20106,4:633-644.
- [33]SHEN H,HE X Z,POOVAIAH C Re,t al.Functional characterization ofthe switchgrass(Panicum virgatum)R2R3-MYB transcription factorPvMYB4 for improvement of lignocellulosic feedstocks[J].New Phytolo-gist,2012,193(1):121-136.
- [34]LEGAY S,LACOMBE E,GOICOECHEA Me,t al.Molecular characteriza-tion of EgMYB,1a putative transcriptional repressor of the lignin biosyn-thetic pathway[J].Plant Science,200,7173:542-549.
- [35]KARPINSKA B,KARLSSON M,SRIVASTAVA Me,t al.MYB transcrip-tion factors are differentially expressed and regulated during secondaryvascular tissue development in hybrid aspenw[J].Plant Molecular Biolo-gy,20045,6:255-270.
- [36]DELUC L,BARRIEU F,MARCHIVE Ce,t al.Characterization of a grape-vine R2R3-MYB transcription factor that regulates the phenylpropanoidpathway[J].Plant Physiology,2006,140:499-511.
- [37]BHARGAVA A,MANSFIELD S D,HALL H Ce,t al.MYB75 functions inregulation of secondary cell wall formation in the Arabidopsis inflorescencestem[J].Plant Physiology,2010,154:1428-1438.
- [38]MIGLARESE M R,RICHARDSON A F,AZIZ Ne,t al.Differential regula-tion of c-Myb-induced transcription activation by a phosphorylation site inthe negative regulatory domain[J].Journal of Biological Chemistry,1996,271(37):22697-22705.
- [39]SCHUBERT S,HORSTMANN S,BARTUSEL T,et al.The cooperation ofB-Myb with the coactivator p300 is orchestrated by cyclins A and D1[J].Oncogene,2004,23:1392-1404.
- [40]ARAKI SI,TO M,SOYANO Te,t al.Mitotic cyclins stimulate the activityof c-Myb-like factors for transactivation of G2/M phase-specific genes intobacco[J].Journal of Biological Chemistry,2004,279(31):32979-32988.
- [41]POPESCU S C,POPESCU G V,BACHAN Se,t al.MAPK target networksin Arabidopsis thaliana revealed using functional protein microarrays[J].Genes&Development,2009,23:80-92.
- [42]MORSE A M,WHETTEN R W,DUBOS Ce,t al.Post-translational modi-fication of an R2R3-MYB transcription factor by a MAP Kinase duringxylem development[J].New Phytologist,2009,183:1001-1013.
- [43]ADAMS-PHILLIPS L,BRIGGS A G,BENT A F.Disruption of poly(ADP-ribosyl)ation mechanism salters responses of Arabidopsis to bioticstress[J].Plant Physiology,2010,152:267-280.
- [44]ZHAO Q,DIXON R A.Transcriptional networks for lignin biosynthesis:more complex than we thought[J].Trends in Plant Science,201,116(4):227-233.
- [45]ZHONG R Q,LEE C H,YE Z H.Evolutionary conservation of the tran-scriptional network regulating secondary cell wall biosynthesis[J].Trendsin Plant Science,2010,15(11):625-632.
- [46]ZHONG R Q,YE Z H.Regulation of cell wall biosynthesis[J].Current O-pinion in Plant Biology,200,710:564-572.
- [47]ZHOU J,SEBASTIAN J,LEE J Y.Signaling and Gene Regulatory Pro-grams in Plant Vascular Stem Cells[J].Genesis,20114,9:885-904.
- [48]ZHONG R Q,YE Z H.Alteration of Auxin Polar Transport in the Arabi-dopsis ifl1 Mutants[J].Plant Physiology,2001,126:549-563.
- [49]GUO X M,ZHANG L,YA H Y,et al.Genetic polymorphism of wheat byIRAP analysis based on retrotransposon Wis2-1 A[J].Agricultural Sci-ence&Technology,2010,11(8):81-83.